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Alumis

Alumis is a precision medicine company focused on the discovery, development, and treatment of autoimmune disorders.
2021
Nov-50
11-50
San Francisco, California, United States
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Innovation

Industry Problem

Patients with immune-mediated diseases need oral medicines that are both effective and more selective than broad immunosuppressants.

R&D Focus

Precision immunology; TYK2 inhibition; data analytics for autoimmune-disease drug discovery.

Innovative Solution

Alumis applies a precision-data analytics platform to discover and develop oral therapies, led by the allosteric TYK2 inhibitor envudeucitinib and other clinical candidates.

Solution Effectiveness

In company-reported Phase 3 psoriasis results, about 65% of patients achieved PASI 90 and more than 40% achieved clear skin at 24 weeks. These are clinical-trial results, not agriculture outcomes.

Investment Funding

Last Funding Stage

Post-IPO Equity

Total Funding Amount

569.M

Last Funding Amount

40.M

Last Funding Date

23-07-2024

Startup Stage

IPO

Lead Investors

Cormorant Asset Management, SR One, Samsara BioCapital, Piper Heartland Healthcare Capital, Omega Funds

People

Founders

About

Alumis develops precision medications to treat autoimmune illnesses. The company’s analytics platform and understanding of immunologic disorders aid in the development of treatments and medications for autoimmune diseases, allowing patients to alleviate suffering and modify their way of life.

Products

Product

Envudeucitinib, A-005 and lonigutamab: investigational medicines for immune-mediated diseases.

Star Product

Envudeucitinib – the most advanced programme and the company’s principal near-term regulatory asset.

Demo Product or Complete Product?

Late-stage clinical products, not an agriculture product. Envudeucitinib is in Phase 3 development; the company indicated a planned FDA filing in the second half of 2026.

Future Plan

Market Expansion

Plans concern clinical development and potential regulatory filings in global pharmaceutical markets, not agriculture.

Investment Funding

Public-company financing is disclosed through SEC filings and investor materials. No agriculture-related fundraising plan applies.

Awards and Recognitions

Participations

Public biotechnology company conducting multiple Phase 2 and Phase 3 clinical programmes.

Media Apperance

Covered in biotechnology and financial media for Phase 3 results and regulatory plans.

M&A and Collabs

Collab

No agriculture collaboration identified. Clinical and research relationships are focused on biotechnology and autoimmune disease.

Acquisitions

Alumis was formed through the evolution of Esker Therapeutics and completed a merger with ACELYRIN in 2025; this is a corporate combination rather than an agriculture acquisition.

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