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List – 31 Biologics Coming Off Patents Between 2022 to 2027

100 Biologics Patents Expiring

Meet The Authors

[vc_row][vc_column][vc_column_text css=”.vc_custom_1642518443755{margin-bottom: 0px !important;}”]Biologics have been observed to be a rapidly evolving area within biotechnology. 

Cancer, autoimmune diseases, and diabetes treatments account for over 60% of the biologics market. Thus making it extremely expensive with prices increasing by the day.

According to the World Health Organization (WHO), these high prices are restricting the healthcare systems from providing affordable, population-wide access to such medicines. This creates a huge space for generic companies to manufacture biosimilars of the originator biologics whose patents have expired.

As a result, generic companies (hey there!) are continuously searching for biologics with a soon-to-be-expired label. To make it easier for them (you), we’ve collated not just the biologics names but also included other information like yearly sales, treatment, dosage, and the brand as well as company names, which could help them (you) easily choose a biologic most profitable to develop a biosimilar. 

If you are interested in biologics patents, then you might also be interested in drug patents that are expiring soon. We have a list of drug patents that are expiring between 2026 to 2030. To get the list, please fill out the form below:


So, without any delay, let’s get to the list of biologics patents expiring between 2022-2027.[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][mk_fancy_title color=”#2878bf” size=”32″ line_height=”80″ font_weight=”bolder” txt_transform=”uppercase” margin_bottom=”0″ font_family=”none”]Biologics Patents Expiration[/mk_fancy_title][mk_divider margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]PERJETA
Pertuzumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$4.73 Billion (2021)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7618631B2 April 16, 2022
US8337856B2 September 30, 2023
US7862817B2 June 1, 2025
US7097840B2 July 25, 2026

[/mk_table][vc_column_text css=”.vc_custom_1642580234990{margin-bottom: 0px !important;}”]Dosage:
Company: Genentech
Treatment: HER2-positive Breast Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]VYROLOGIX
Leronlimab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$576 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7666419B2 February 21, 2023
US7851600B2 February 21, 2023
US7122185B2 June 1, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642594678277{margin-bottom: 0px !important;}”]Dosage:
Company: Cytodyn Inc.
Treatment: HIV Infection[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]STELARA
Ustekinumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$9.13 Billion (2021)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7279157B2 January 13, 2022
US9409984B2 February 27, 2022
US7166285B2 May 3, 2022
US8080247B2 August 2, 2022
US6902734B2 September 25, 2023

[/mk_table][vc_column_text css=”.vc_custom_1642509106163{margin-bottom: 0px !important;}”]Dosage: Injection
Company: Janssen Pharmaceuticals
Treatment: Plaque Psoriasis and Psoriatic Arthritis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]BENLYSTA
Belimumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$747 Million (2019)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7605236B2 August 5, 2022
US7220840B2 July 11, 2023
US7879328B2 July 17, 2023
US7138501B2 March 9, 2025

[/mk_table][vc_column_text css=”.vc_custom_1642582094229{margin-bottom: 0px !important;}”]Dosage: Injection
Company: GlaxoSmithKline
Treatment: Systemic Lupus Erythematosus[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]CYRAMZA
Ramucirumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$1.033 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8057791B2 December 07, 2023
US7498414B2 January 31, 2026

[/mk_table][vc_column_text css=”.vc_custom_1642596991513{margin-bottom: 0px !important;}”]Dosage:
Company: ImClone Systems Inc.
Treatment: Solid Tumors[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]ELELYSO
Taliglucerase Alfa[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8227230B2 February 24, 2024
US8741620B2 February 24, 2024
US9220737B2 February 24, 2024
US7951557B2 July 01, 2025
US8790641B2 October 18, 2025

[/mk_table][vc_column_text css=”.vc_custom_1642600575208{margin-bottom: 0px !important;}”]Dosage:
Company: Protalix and Pfizer
Treatment: Type 1 Gaucher disease[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]IXIARO
Japanese Encephalitis Vaccine[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$106.75 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US6309650 December 30, 2022

[/mk_table][vc_column_text css=”.vc_custom_1642588923622{margin-bottom: 0px !important;}”]Dosage: Injection
Company: BIKEN and Sanofi Pasteur
Treatment: Japanese encephalitis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]JETREA
Ocriplasmin[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$7.8 Million (2016)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7445775 October 17, 2026

[/mk_table][vc_column_text css=”.vc_custom_1642602689331{margin-bottom: 0px !important;}”]Dosage: Intravitreal Injection
Company: ThromboGenics
Treatment: Symptomatic Vitreomacular Adhesion[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]KADCYLA
Trastuzumab Emtansine[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$960 Million (2018)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7618631B2 April 16, 2022
US8337856B2 September 30, 2023
US7862817B2 June 1, 2025
US7097840B2 July 25, 2026

[/mk_table][vc_column_text css=”.vc_custom_1642580392748{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Genentech
Treatment: HER2-positive Breast Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]KALBITOR
Ecallantide[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$67.3 Million (2017)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7276480 June 6, 2023

[/mk_table][vc_column_text css=”.vc_custom_1642594844468{margin-bottom: 0px !important;}”]Dosage: Injection
Company: Takeda Pharmaceutical
Treatment: Hereditary Angioedema[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]MYALEPT
Metreleptin[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$71.4 Million (2018)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8318666B2 October 22, 2022
US7183254B2 July 17, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642582391831{margin-bottom: 0px !important;}”]Dosage: Injection
Company: Amryt Pharmaceutical
Treatment: Dyslipidemia[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]NPLATE
Romiplostim[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$227 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US6835809 January 19, 2022

[/mk_table][vc_column_text css=”.vc_custom_1642509298504{margin-bottom: 0px !important;}”]Dosage: Injection
Company: Amgen
Treatment: Low blood platelet counts[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]TANZEUM
Albiglutide[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$160 Million (2016)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7238660B2 December 23, 2022
US7238667B2 December 23, 2022
US8071539B2 December 23, 2022
US9221896B2 December 23, 2022
US9296809B2 December 23, 2022
US7977306B2 January 2, 2023
US7799759B2 February 11, 2023
US8993517B2 February 12, 2023
US7189690B2 October 2, 2023
US7592010B2 December 1, 2023
US7521424B2 January 20, 2024
US8287859B2 February 11, 2024
US8012464B2 May 21, 2024
US8143026B2 February 9, 2025
US8211439B2 April 11, 2025
US7847079B2 October 4, 2025
US7141547B2 April 22, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642588112761{margin-bottom: 0px !important;}”]Dosage: Injection
Company: GlaxoSmithKline
Treatment: Type 2 Diabetes[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]VICTOZA
Liraglutide[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$2.7 Billion (2018)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US6268343 August 22, 2022

[/mk_table][vc_column_text css=”.vc_custom_1642582216050{margin-bottom: 0px !important;}”]Dosage: Injection
Company: Novo Nordisk
Treatment: Type 2 Diabetes[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]YERVOY
Ipilimumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$1.7 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US6984720 February 8, 2022

[/mk_table][vc_column_text css=”.vc_custom_1642518931139{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Bristol‑Myers Squibb
Treatment: Melanoma[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row]

[vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]DARZALEX
Daratumumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$4.1 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7829673B2 August 27, 2026
US9187565B2 December 5, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642602528474{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Genmab
Treatment: Myeloma[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]BLINCYTO
Blinatumomab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$103 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7635472B2 November 28, 2025

[/mk_table][vc_column_text css=”.vc_custom_1642602028625{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Micromet (acquired by Amgen)
Treatment: Acute Lymphoblastic Leukemia[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]CIMZIA
Certolizumab Pegol[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$2.04 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7186820B2 February 3, 2022
US7977464B2 February 13, 2022
US7012135B2 February 13, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642579379068{margin-bottom: 0px !important;}”]Dosage: Subcutaneous Injection
Company: UCB
Treatment: Crohn’s Disease, Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]ILARIS
Canakinumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$576 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7446175B2 December 22, 2022

[/mk_table][vc_column_text css=”.vc_custom_1642587668959{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Novartis
Treatment: Systemic Juvenile Idiopathic Arthritis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]SIMPONI
Golimumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$576 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7521206B2 March 20, 2022
US8241899B2 November 3, 2022
US7250165B2 February 3, 2024
US7691378B2 September 19, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642580072956{margin-bottom: 0px !important;}”]Dosage: Subcutaneous Injection
Company: Janssen Biotech
Treatment: Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]TRULICITY
Dulaglutide[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$5.07 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US10369003B2 October 15, 2024
US10376376B2 October 15, 2024
US10610371B2 October 15, 2024
US11083591B2 October 15, 2024
US9056018B2 October 15, 2024
US9867712B2 October 15, 2024
US10695187B2 June 28, 2025
US8273854B2 May 15, 2026
US10130493B2 July 17, 2026
US8535379B2 December 13, 2026
US11135072B2 April 11, 2027
US7452966B2 December 7, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642601376296{margin-bottom: 0px !important;}”]Dosage: Subcutaneous Injection
Company: Eli Lilly and Company
Treatment: Type 2 Diabetes[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]ZALTRAP
Aflibercept[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$15.88 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7399612B2 November 6, 2023
US7279159B2 November 11, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642596733679{margin-bottom: 0px !important;}”]Dosage: Intravitreal Injection
Company: Regeneron Pharmaceuticals
Treatment: Wet Macular Degeneration and Metastatic Colorectal Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]SYLVANT
Siltuximab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7612182B2 October 26, 2022
US7955597B2 October 26, 2022
US7833786B2 June 7, 2023
US7291721B2 September 13, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642582534148{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Eusa Pharma
Treatment: Metastatic Renal Cell Cancer, Prostate Cancer, and Castleman’s Disease[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]LARTRUVO
Olaratumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$304.7 Million (2018)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8574578B2 June 19, 2026
US8128929B2 December 20, 2027

[/mk_table][vc_column_text css=”.vc_custom_1642666838843{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Eli Lilly and Company
Treatment: Solid Tumors[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]OPDIVO
Nivolumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$7.92 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US9393301B2 July 2, 2023
US8168179B2 July 2, 2023
US9067999B1 July 2, 2023
US9073994B2 July 2, 2023
US9439962B2 July 2, 2023
US9402899B2 February 5, 2024
US7595048B2 August 8, 2024
US8728474B2 August 8, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642595073046{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Bristol‑Myers Squibb
Treatment: Different Types of Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]PORTRAZZA
Necitumumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7598350B2 March 21, 2025

[/mk_table][vc_column_text css=”.vc_custom_1642601877572{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Eli Lilly and Company
Treatment: Metastatic Squamous Non-small Cell Lung Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]PROLIA
Denosumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$4.6 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8409578B2 June 25, 2022
US8058418B2 November 30, 2023
US7364736B2 February 19, 2025

[/mk_table][vc_column_text css=”.vc_custom_1642581937003{margin-bottom: 0px !important;}”]Dosage: Subcutaneous Injection
Company: Amgen
Treatment: Osteoporosis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]TALTZ
Ixekizumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$1.78 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8110191B2 December 5, 2026
US7838638B2 February 4, 2030

[/mk_table][vc_column_text css=”.vc_custom_1642602837379{margin-bottom: 0px !important;}”]Dosage: Subcutaneous Injection
Company: Eli Lilly and Company
Treatment: Autoimmune Diseases[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]ARANESP
Darbepoetin Alfa[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$629 Million (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7217689B1 May 15, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642601036160{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Amgen
Treatment: Anemia[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]EYLEA
Aflibercept[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
$8.36 Billion (2020)[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US7279159B2 November 11, 2024

[/mk_table][vc_column_text css=”.vc_custom_1642601769098{margin-bottom: 0px !important;}”]Dosage: Intravitreal Injection
Company: Regeneron Pharmaceuticals
Treatment: Wet Macular Degeneration and Metastatic Colorectal Cancer[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]ARZERRA
Ofatumumab[/mk_fancy_title][/vc_column_inner][vc_column_inner width=”1/2″][mk_fancy_title color=”#777777″ size=”16″ font_family=”none”]Sales:
[/mk_fancy_title][/vc_column_inner][/vc_row_inner][vc_accordions action_style=”toggle-action”][vc_accordion_tab icon=”mk-moon-inject-2″ title=”More information about this Drug”][vc_row_inner][vc_column_inner width=”1/12″][/vc_column_inner][vc_column_inner width=”10/12″][mk_table]

Patents Expiration Date
US8529902B2 August 2, 2030

[/mk_table][vc_column_text css=”.vc_custom_1642602923884{margin-bottom: 0px !important;}”]Dosage: Intravenous Infusion
Company: Genmab
Treatment: Multiple Sclerosis[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/12″][/vc_column_inner][/vc_row_inner][/vc_accordion_tab][/vc_accordions][mk_divider style=”thin_solid” margin_bottom=”40″][/vc_column][/vc_row][vc_row][vc_column][vc_column_text css=”.vc_custom_1642519179025{margin-bottom: 0px !important;}”]

Conclusion

Earlier we released a list of 91 drug patents expiring between 2020 to 2022. And while small molecule drugs still dominate the global pharmaceutical market in terms of numbers, many of the most promising new therapies for previously intractable diseases are a result of biologics. Biologics are thus becoming increasingly important to the pharmaceutical market. But having this list is one thing and using it is another.

Developing biosimilars is not going to be as smooth sailing. Generic companies will likely have to face many threats and stiff legal battles depending on the biologic they choose.

With proper threat analysis, companies can save themselves from this torment. Wanna know all about it? Just fill out the form below and we’ll get back to you in no time.

List curated by: Divya Goyal, Life Science Team Authored By: Nidhi, Marketing.

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