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 List – 59 Drug Patents that are Expiring in 2027

List – 59 Drug Patents that are Expiring in 2027

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Procysbi
Cysteamine

PatentsExpiration Date
US9925158January 26, 2027
US9925157January 26, 2027
US9925156January 26, 2027

Dosage: Oral, Eye drops
Company: Horizon Therapeutics plc
Ingredients: CYSTEAMINE BITARTRATE
Treatment: Cystinosis

Ongentys
Opicapone

PatentsExpiration Date
US8907099May 12, 2027
US8168793April 2, 2029
US9630955December 12, 2032

Dosage: Oral
Company: Neurocrine Biosciences, Inc
Ingredients: OPICAPONE
Treatment: Parkinson’s Disease

Iclusig
Ponatinib

PatentsExpiration Date
US8114874January 24, 2027
US9493470December 12, 2033
US11192897December 12, 2033

Dosage: Oral
Company: Takeda Pharmaceuticals
Ingredients: PONATINIB HYDROCHLORIDE
Treatment: Chronic Myeloid Leukemia (CML) and Philadelphia chromosome-positive (Ph+), Acute Lymphoblastic Leukemia (ALL).

Ovide
Malathion

PatentsExpiration Date
US7560445February 1, 2027

Dosage: Topical
Company: Taro Pharmaceuticals
Ingredients: MALATHION
Treatment: Pediculosis

Altabax
Retapamulin

PatentsExpiration Date
US7875630February 14, 2027

Dosage: Topical
Company: GlaxoSmithKline
Ingredients: RETAPAMULIN
Treatment: Impetigo

Stribild
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil

PatentsExpiration Date
US7176220February 27, 2027
US7635704April 26, 2027
US8981103April 26, 2027

Dosage: Oral
Company: Gilead Sciences Inc
Ingredients: COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE
Treatment: HIV/AIDS

Altabax
Retapamulin

PatentsExpiration Date
US7176220February 27, 2027
US7635704April 26, 2027
US8981103April 26, 2027

Dosage: Oral
Company: Wyeth Pharmaceuticals Llc
Ingredients: BAZEDOXIFENE ACETATE; ESTROGENS, CONJUGATED
Treatment: Hot Flashes, Osteoporosis

Stribild
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil

PatentsExpiration Date
US7176220February 27, 2027
US7635704April 26, 2027
US8981103April 26, 2027

Dosage: Oral
Company: Gilead Sciences Inc
Ingredients: COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE
Treatment: HIV/AIDS

Duavee
Conjugated Estrogens/Bazedoxifene

PatentsExpiration Date
US7683051March 10, 2027

Dosage: Oral
Company: Wyeth Pharmaceuticals Llc
Ingredients: BAZEDOXIFENE ACETATE; ESTROGENS, CONJUGATED
Treatment: Hot Flashes, Osteoporosis

Zolinza
Vorinostat

PatentsExpiration Date
US7456219March 11, 2027

Dosage: Oral
Company: Merck & Co
Ingredients: VORINOSTAT
Treatment: Cutaneous T Cell Lymphoma (CTCL)

Erleada
Apalutamide

PatentsExpiration Date
US9388159March 27, 2027
US8445507September 15, 2030
US9481663June 4, 2033

Dosage: Oral
Company: Janssen-Cilag International NV
Ingredients: APALUTAMIDE
Treatment: Prostate Cancer

Varubi
Rolapitant

PatentsExpiration Date
US8178550April 4, 2027
US7049320August 19, 2028

Dosage: Oral
Company: Tesaro
Ingredients: ROLAPITANT HYDROCHLORIDE
Treatment: Chemotherapy-induced Nausea And Vomiting (CINV)

Symdeko
Tezacaftor-ivacaftor

PatentsExpiration Date
US10239867April 9, 2027
US8623905May 1, 2027
US7645789May 1, 2027
US7776905June 3, 2027

Dosage: Oral
Company: Vertex Pharmaceuticals Inc
Ingredients: IVACAFTOR; IVACAFTOR, TEZACAFTOR
Treatment: Cystic Fibrosis

Synjardy
Empagliflozin/Metformin

PatentsExpiration Date
US7713938April 15, 2027
US7579449August 1, 2028

Dosage: Oral
Company: Boehringer Ingelheim/Eli Lilly And Company
Ingredients: EMPAGLIFLOZIN; METFORMIN HYDROCHLORIDE
Treatment: Type 2 Diabetes

Savaysa
Edoxaban

PatentsExpiration Date
US7365205April 18, 2027

Dosage: Oral
Company: Daiichi Sankyo
Ingredients: EDOXABAN TOSYLATE
Treatment: Venous Thromboembolism

Amyvid
Florbetapir (18f)

PatentsExpiration Date
US8506929April 30, 2027
US7687052April 30, 2027

Dosage: Intravenous Injection
Company: Avid Radiopharmaceuticals
Ingredients: FLORBETAPIR F-18
Treatment: Alzheimer’s

Mekinist
Trametinib

PatentsExpiration Date
US7378423May 29, 2027

Dosage: Oral
Company: Novartis
Ingredients: TRAMETINIB DIMETHYL SULFOXIDE
Treatment: Melanoma

Altavera/Alysena/Amethyst
Ethinylestradiol/Levonorgestrel

PatentsExpiration Date
US7838042June 1, 2027

Dosage: Oral
Company: Bayer Healthcare Pharmaceuticals
Ingredients: ETHINYL ESTRADIOL; LEVONORGESTREL
Treatment: Contraception

Xadago
Safinamide

PatentsExpiration Date
US8278485June 8, 2027
US8076515December 10, 2028

Dosage: Oral
Company: Newron Pharmaceuticals
Ingredients: SAFINAMIDE MESYLATE
Treatment: Parkinson’s Disease

Xadago
Safinamide

PatentsExpiration Date
US8278485June 8, 2027
US8076515December 10, 2028

Dosage: Oral
Company: Newron Pharmaceuticals
Ingredients: SAFINAMIDE MESYLATE
Treatment: Parkinson’s Disease

Antizol
Fomepizole

PatentsExpiration Date
US7553863June 30, 2027

Dosage: Intravenous
Company: Paladin Labs
Ingredients: FOMEPIZOLE
Treatment: Ethylene Glycol And Methanol Poisoning

Vokanamet
Canagliflozin/Metformin

PatentsExpiration Date
US7943788July 14, 2027
US8513202December 3, 2027
US7943582February 26, 2029

Dosage: Intravenous
Company: Janssen-cilag International Nv
Ingredients: CANAGLIFLOZIN; METFORMIN HYDROCHLORIDE
Treatment: Type 2 Diabetes

Asacol/Lialda/Pentasa
Mesalazine

PatentsExpiration Date
US7645801July 24, 2027

Dosage: Oral, Rectal
Company: Tillotts Pharma Ag.
Ingredients: MESALAMINE
Treatment: Ulcerative Colitis And Crohn’s Disease

Daklinza
Daclatasvir

PatentsExpiration Date
US9421192August 8, 2027
US8642025August 11, 2027
US8329159July 24, 2029
US8629171June 13, 2031

Dosage: Oral
Company: Bristol-Myers Squibb
Ingredients: DACLATASVIR DIHYDROCHLORIDE
Treatment: Hepatitis C

Xtandi
Enzalutamide

PatentsExpiration Date
US7709517August 13, 2027

Dosage: Oral
Company: Astellas Pharma Inc.
Ingredients: ENZALUTAMIDE
Treatment: Prostate Cancer

Azilect
Rasagiline

PatentsExpiration Date
US7815942August 27, 2027

Dosage: Oral
Company: Teva Pharmaceutical
Ingredients: RASAGILINE MESYLATE
Treatment: Parkinson’s Disease

Tivicay
Dolutegravir

PatentsExpiration Date
US8129385October 5, 2027
US9242986December 8, 2029
US10426780January 24, 2031

Dosage: Oral
Company: Viiv Healthcare
Ingredients: DOLUTEGRAVIR SODIUM
Treatment: HIV/AIDS

Imcivree
Setmelanotide

PatentsExpiration Date
US9458195October 13, 2027
US8039435October 13, 2027

Dosage: Subcutaneous
Company: Rhythm Pharmaceutical
Ingredients: SETMELANOTIDE ACETATE
Treatment: Genetic Obesity

Xcopri
Cenobamate

PatentsExpiration Date
US7598279October 30, 2027

Dosage: Subcutaneous
Company: SK Biopharmaceuticals
Ingredients: CENOBAMATE
Treatment: Partial Epilepsies

Pylarify
Piflufolastat F-18

PatentsExpiration Date
US10793596November 12, 2027
US10017536November 12, 2027
US8536131November 12, 2027
US7727963November 12, 2027
US7713937November 12, 2027
US7402564November 12, 2027

Dosage: Intravenous
Company: Progenics Pharmaceuticals
Ingredients: PIFLUFOLASTAT F-18
Treatment: Prostate Cancer Metastasis

Korsuva
Difelikefalin

PatentsExpiration Date
US8487129November 7, 2027
US9861713July 31, 2029
US8778305September 21, 2030
US10947197June 9, 2037

Dosage: Intravenous
Company: Cara Therapeutics
Ingredients: DIFELIKEFALIN ACETATE
Treatment: Itching

Empaveli
Pegcetacoplan

PatentsExpiration Date
US9169307November 18, 2027
US7989589December 4, 2027
US7888323December 4, 2027
US10125171August 2, 2033
US10875893November 15, 2033
US10035822November 15, 2033

Dosage: Subcutaneous
Company: Apellis Pharmaceuticals/Swedish Orphan Biovitrum
Ingredients: PEGCETACOPLAN
Treatment: Paroxysmal Nocturnal Hemoglobinuria (PNH)

Tabrecta
Capmatinib

PatentsExpiration Date
US8461330November 19, 2027
US7767675November 19, 2027
US8420645June 5, 2031
US10596178July 22, 2035

Dosage: Subcutaneous
Company: Novartis Pharmaceuticals
Ingredients: CAPMATINIB HYDROCHLORIDE
Treatment: Non-small Cell Lung Cancer (NSCLC)

Turalio
Pexidartinib

PatentsExpiration Date
US9169250November 21, 2027
US8404700November 21, 2027
US8722702November 21, 2027
US7893075October 13, 2028
US10730876May 5, 2036
US9802932May 5, 2036

Dosage: Subcutaneous
Company: Daiichi Sankyo Company
Ingredients: PEXIDARTINIB HYDROCHLORIDE
Treatment: Tenosynovial Giant Cell Tumor (TGCT)

Toradol/Biorolac
Ketorolac

PatentsExpiration Date
US8008338November 24, 2027
US7842714August 15, 2029

Dosage: Oral, Intramuscular, Intravenous, Eye drops, Nasal spray
Company: Cadila Healthcare Limited
Ingredients: KETOROLAC TROMETHAMINE
Treatment: Pain

Entresto
Sacubitril/Valsartan

PatentsExpiration Date
US8877938November 27, 2027

Dosage: Oral
Company: Novartis
Ingredients: SACUBITRIL; VALSARTAN
Treatment: Heart Failure

Xermelo
Telotristat Ethyl

PatentsExpiration Date
US7709493December 11, 2027
US7553840December 11, 2027
US8193204February 27, 2031

Dosage: Oral
Company: Lexicon Pharmaceuticals 
Ingredients: TELOTRISTAT ETIPRATE
Treatment: Carcinoid Syndrome Diarrhea

Jakafi
Ruxolitinib

PatentsExpiration Date
US8415362December 24, 2027
US7598257December 24, 2027
US8722693June 12, 2028

Dosage: Oral, Topical
Company: Incyte Corp/Novartis
Ingredients: RUXOLITINIB PHOSPHATE
Treatment: Myelofibrosis

Nexavar
Sorafenib

PatentsExpiration Date
US8877933December 24, 2027

Dosage: Oral, Topical
Company: Bayer/Onyx Pharmaceuticals
Ingredients: SORAFENIB TOSYLATE
Treatment: Renal Cell Carcinoma

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